MATHEMATICAL BIOLOGY
Parallel Coordinates plot from the recently published "Koshy-Chenthittayil, S. et al. ‘A Computational Framework for Finding Parameter Sets Associated with Chaotic Dynamics’. Journal: In Silico Biology, vol. 14, no. 1-2, pp. 41-51, 2020
https://content.iospress.com/articles/in-silico-biology/isb200476
Research Skills and Interests
Fields of expertise include Chaos Theory, Agent-based models with Java and Netlogo, Numerical Analysis with Maple, MATLAB, Statistics with R and SAS
Interested in Chaos theory for biologically relevant systems, mathematical models based on clinical data for diseases.
Well versed in interdisciplinary research.
Ad-hoc peer reviewer of relevant articles on mathematical biology.
PUBLICATIONS
Archambault, L.; Koshy-Chenthittayil, S.; Thompson, A.; Dongari-Bagtzoglou, A.; Laubenbacher, R.; & Mendes, P. (2021). Understanding Lactobacillus paracasei and Streptococcus oralis biofilm interactions through agent-based modeling. mSphere 6(6) https://doi.org/10.1128/mSphere.00875-21. Code available at https://github.com/skoshyc/StrepLactoBiofilmModeling
Koshy-Chenthittayil, S.; Mendes, P; Laubenbacher R.L. (2021). Optimization of agent-based models through dimension reduction: a case study in microbial ecology. Letters In Biomathematics, 8(1), 167-178
https://lettersinbiomath.journals.publicknowledgeproject.org/index.php/lib/article/view/431. Code available at https://github.com/skoshyc/optimization_Pareto
Koshy-Chenthittayil, S.; Archambault, L.; Senthilkumar, D.; Laubenbacher, R.; Mendes, P.; Dongari-Bagtzoglou, A. (2021) Agent Based Models of Polymicrobial Biofilms and the Microbiome—A Review. Microorganisms, 9, 417. https://doi.org/10.3390/microorganisms9020417
Koshy-Chenthittayil, S.; Dimitrova, E.; Jenkins E.W.; Dean, B.C. (2021). A Computational Framework for Finding Parameter Sets Associated with Chaotic Dynamics In Silico Biology- vol. 14, no. 1-2, pp. 41-51, 2020 https://content.iospress.com/articles/in-silico-biology/isb200476. Code available at https://github.com/skoshyc/Computational-Framework-Chaotic-Dynamics
Sun, M.; Koshy-Chenthittayil, S.; & D’Souza, N. F. (2020). Quantitative Medicine and Reflection on Summer Research in Mathematical Biology. Harvard Educational Review, 90(2), 322-330.
Koshy-Chenthittayil, S. & Dimitrova, E. (2020). From Chaos to Permanence Using Control Theory. Advances in Mathematical Sciences, 85-106.
Dean, B.C.; Dimitrova, E.; Galande, A.; Jenkins, E.W.; Koshy, S. (2016). Determining Parameters Leading to Chaotic Dynamics in Systems https://arxiv.org/abs/1604.06951
PRESENTATIONS
‘Streptococcus oralis and Lactobacillus paracasei interactions through the lens of an agent-based model’ – Invited talk, 6th International Symposium on Systems Biology of Microbial Infections, Nov 2021,
https://asb-conference.hki-jena.de/event/11/page/15-invited-speakers'Application of an agent-based model to biofilms' – Invited Talk, AWM Salon Series, Muhlenberg College, March 2021
'Using agent-based models to understand biofilm interactions' - Invited Talk, Mathematics Continued Conference, UConn, Oct 2020 (Virtual due to COVID-19)
'A mathematical modeling journey into biofilms'-Invited Talk, Adelphi AMS Seminar Series, Adelphi University, Oct 2020 (Virtual due to COVID-19)
'Optimization of agent-based models of mixed-species biofilms'- SIAM conference on the Life Sciences July 2020- Canceled due to COVID-19
‘Agent-based modeling of multi-species biofilm and its optimization’ presentation at Joint Mathematics Meeting (JMM) Jan 2020.
‘The dynamic nature of functional brain networks of emotional regulation’ presentation at Biology and Medicine in Mathematics (BAMM) May 2018
‘Permanence and Chaos in Dynamical Systems’ presentation at SIAM conference on the Life Sciences July 2016
Poster presentation ‘Determination of Parameters for Chaos in Dynamical Systems’ at Séminaire de Mathématiques Supérieures: Dynamics of Biological Systems-Uty of Alberta June 2016; SIAM conference on the Life Sciences July 2016; Algebraic and Combinatorial Approaches in Systems Biology 2015 Conference in UCONN Health